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LUBRICATION CONDITIONS FOR WEAR SIMULATION IN ARTIFICIAL HIP REPLACEMENTS

机译:人工髋关节置换中磨损模拟的润滑条件

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摘要

It is essential to evaluate the wear behavior of joint replacement materials and designs. While synovial fluid is the biological joint lubricant, it is present in too small quantities to use for wear simulations. A variety of lubricants have been used, such as water, saline solutions, synovial fluid components (hyaluronic acid, lubricin, and phospholipids), serum and custom-made lubricants. Studies from our Loma Linda University Medical Center lab and others have explored the benefits and deficiencies of these pseudo-synovial fluids. Serum is used extensively as the lubricant because its results most closely match clinical results with polyethylene bearings. Laboratory experiments have explored the effects of serum with differences of proteins (concentration, type, and ratio), volume, viscosity, temperature, and additives and their wear response. The properties of current lubricants, in particular the roles of proteins, are the current focus in the search for an ideal joint analogue fluid.
机译:评估关节置换材料和设计的磨损性能至关重要。滑液是生物关节润滑剂,但存在量太少,无法用于磨损模拟。已经使用了多种润滑剂,例如水,盐溶液,滑液成分(透明质酸,润滑脂和磷脂),血清和定制润滑剂。我们的洛马琳达大学医学中心实验室和其他机构的研究探索了这些假性滑液的好处和不足。血清被广泛用作润滑剂,因为其结果与聚乙烯轴承的临床结果最接近。实验室实验已经探索了血清对蛋白质(浓度,类型和比例),体积,粘度,温度和添加剂及其磨损响应的影响。当前润滑剂的特性,特别是蛋白质的作用,是寻找理想的关节模拟液的当前焦点。

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