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Improved Biphasic Pulsing Power Efficiency with Pt-Ir Coated Microelectrodes

机译:Pt-Ir涂层微电极改善了两相脉冲功率效率

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摘要

Neuromodulation devices such as deep brain stimulators (DBS), spinal cord stimulators (SCS) and cochlear implants (CIs) use electrodes in contact with tissue to deliver electrical pulses to targeted cells. In general, the neuromodulation industry has been evolving towards smaller, less invasive devices Improving power efficiency of these devices can reduce battery storage requirements. Neuromodulation devices can realize significant power savings if the impedance to charge transfer at the electrode-tissue interface can be reduced. High electrochemical impedance at the surface of stimulation microelectrodes results in larger polarization voltages. Decreasing this polarization voltage response can reduce power required to deliver the current pulse. One approach to doing this is to reduce the electrochemical impedance at the electrode surface. Previously we have reported on a novel electrochemically deposited 60:40% platinum-iridium (Pt-Ir) electrode material that lowered the electrode impedance by two orders of magnitude or more. This study compares power consumption of an electrochemically deposited Pt-Ir stimulating microelectrode to that of standard Pt-Ir probe microelectrode produced using conventional techniques. Both electrodes were tested using in-vitro in phosphate buffered saline (PBS) solution and in-vivo (live rat) models.
机译:神经调节装置,例如深脑刺激器(DBS),脊髓刺激器(SCS)和耳蜗植入物(CIs),使用与组织接触的电极将电脉冲传递到目标细胞。通常,神经调节行业一直在朝着更小,侵入性更小的设备发展。提高这些设备的电源效率可以减少电池的存储需求。如果可以减小电极组织界面上电荷转移的阻抗,神经调节设备可以实现显着的节能效果。刺激微电极表面的高电化学阻抗导致更大的极化电压。减小该极化电压响应可以降低传递电流脉冲所需的功率。一种这样做的方法是降低电极表面的电化学阻抗。以前,我们已经报道了一种新型的电化学沉积60:40%铂铱(Pt-Ir)电极材料,该材料将电极阻抗降低了两个数量级或更多。这项研究将电化学沉积的Pt-Ir刺激微电极的功耗与使用常规技术生产的标准Pt-Ir探针微电极的功耗进行了比较。使用磷酸盐缓冲盐水(PBS)溶液中的体外和活体(活大鼠)模型测试两个电极。

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  • 会议地点 Boston MA(US)
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    Mork Family Department of Chemical Engineering and Materials Science, University of Southern California, Los Angeles, California, USA,Department of Ophthalmology, University of Southern California, Los Angeles, California, USA;

    Department of Biomedical Engineering, University of Southern California, Los Angeles, California, USA;

    Department of Ophthalmology, University of Southern California, Los Angeles, California, USA;

    Mork Family Department of Chemical Engineering and Materials Science, University of Southern California, Los Angeles, California, USA;

    Department of Ophthalmology, University of Southern California, Los Angeles, California, USA Department of Biomedical Engineering, University of Southern California, Los Angeles, California, USA;

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