Raman Spectroscopic Characterization on Cervical Neoplasm in Biopsy Direction

摘要

Raman spectroscopy was applied to distinguish the spectroscopic information between normal cervical tissues (14) and cervical neoplasia (17), including low grade squamous intraepithelial lesions (6) and high grade squamous intraepithelial lesions (11). Standard pathological sections of these cervical tissues were measured from superficial to stroma layers. We have normalized significant Raman peaks, 1250 and 1579-1656 cm~(-1) by taking a ratio over a stationary Raman at 1004 cm~(-1), and successfully discriminated between normal and neoplasm cervical tissues.