External and internal mass transfer in biocatalyst particle for a stationary basket bioreactor: Topic: Biotechnologies and molecular bioengineering

摘要

The paper presents the results of the study on the external and internal mass transfers of substrate (glucose) using a bioreactor with stationary basket beds of immobilized Saccharomyces cerevisiae cells. By combining the substrate mass balance for a single particle of biocatalyst and the kinetic model for glucose consumption, specific mathematical models have been developed for estimating the glucose mass flows in the liquid boundary layer surrounding the particle and inside the particle. The presented results are the first unitary approach of the aspects of substrate mass transfer in a basket bed of immobilized biocatalysts, the proposed models being original and complex.