Degradation kinetic differences among high energy physical treatments and their applications in chitosan production with concurrent ultrafiltration treatment

摘要

Degradation kinetic differences in microfluidization, sonolysis, and shearing treatments among high energy physical treatments in chitosan were study. Solution concentration, temperature, reaction time and with or without concurrent ultrafiltration treatment for fragment removal are factors that affect the degradation rate constant The cause of these operation conditions and their effect on chitosan degradation rate constant were compared. Different operation conditions of each treatments resulted in various solution viscosity, easiness in dissipation of cavitation, entanglement and stretching in turn resulted in different effectiveness of degradation by different degradation mechanisms. The rationale of applying those physical methods in practical chitosan production was proposed.