首页> 外文会议>26th European conference on biomaterials 2014 >Antitumor Efficacy of Radioactive Holmium (~(166)Ho) Containing Silica Sol-gel Glass Granules on Osteosarcoma (MG-63) and Breast Cancer (MCF-7) Cells in Vitro

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Antitumor Efficacy of Radioactive Holmium (~(166)Ho) Containing Silica Sol-gel Glass Granules on Osteosarcoma (MG-63) and Breast Cancer (MCF-7) Cells in Vitro

机译：放射性Hol（〜（166）Ho）二氧化硅溶胶-凝胶玻璃颗粒对骨肉瘤（MG-63）和乳腺癌（MCF-7）细胞的体外抗肿瘤作用

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Based on these in vitro results, ~（166）Ho containing silica sol-gel glass granules have the expected tumor-killing efficacy. This injectable bioresorbable material could be a valuable addition to percutaneous osteoplasty of bone metastases. After decay of the radioactivity, the composite could act as an osteoconductive material for restoration of the bone stock.

机译：基于这些体外结果，〜（166）Ho含硅溶胶凝胶玻璃颗粒具有预期的杀灭肿瘤的功效。这种可注射的生物可吸收材料可能是骨转移的经皮骨成形术的宝贵补充。放射性衰减后，复合材料可作为骨传导材料来恢复骨质。

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《26th European conference on biomaterials 2014》|2014年|264-264|共1页
会议地点 Liverpool(GB)
作者
Riku Alaranta; Jessica J Alm; Kaisa Lehtimaeki; Heimo Ylaenen; Tapio Ollonqvist; Hannu T Aro;
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Orthopaedic Research Unit, Department of Orthopaedic Surgery and Traumatology, University of Turku, Finland;

Orthopaedic Research Unit, Department of Orthopaedic Surgery and Traumatology, University of Turku, Finland;

Orthopaedic Research Unit, Department of Orthopaedic Surgery and Traumatology, University of Turku, Finland;

Turku Biomaterials Centre, University of Turku, Finland;

Department of Oncology, Turku University Hospital, Finland;

Orthopaedic Research Unit, Department of Orthopaedic Surgery and Traumatology, University of Turku, Finland;

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1. Intratumoral injection of radioactive holmium ( Ho-166) microspheres for treatment of oral squamous cell carcinoma in cats [J] . van Nimwegen S. A., Bakker R. C., Kirpensteijn J., Veterinary and Comparative Oncology . 2018,第1期

机译：妥善注射放射性钬（HO-166）微球，用于治疗猫口腔鳞状细胞癌
2. Hesperidin exhibits in vitro and in vivo antitumor effects in human osteosarcoma MG-63 cells and xenograft mice models via inhibition of cell migration and invasion, cell cycle arrest and induction of mitochondrial-mediated apoptosis [J] . Du Guang-Yu, He Sheng-Wei, Zhang Lu, Oncology letters . 2018,第5aPta2期

机译：Hesperidin通过抑制细胞迁移和侵袭，细胞周期停滞和线粒体介导的细胞凋亡，在人骨肉瘤Mg-63细胞和异种移植小鼠模型中具有体外和体内抗肿瘤作用。
3. Intratumoral Administration of Holmium-166 Acetylacetonate Microspheres: Antitumor Efficacy and Feasibility of Multimodality Imaging in Renal Cancer [J] . Wouter Bult, Stephanie G. C. Kroeze, Mattijs Elschot, PLoS One . 2013,第1期

机译：166166乙酰丙酮ate微球的瘤内给药：肾癌的抗肿瘤功效和多模态成像的可行性。
4. Antitumor Efficacy of Radioactive Holmium (~(166)Ho) Containing Silica Sol-gel Glass Granules on Osteosarcoma (MG-63) and Breast Cancer (MCF-7) Cells in Vitro [C] . Riku Alaranta, Jessica J Alm, Kaisa Lehtimaki, European Conference on Biomaterials . 2014

机译：放射性钬（〜（166）孔）含有二氧化硅溶胶 - 凝胶玻璃颗粒的抗肿瘤效果（Mg-63）和乳腺癌（MCF-7）细胞体外
5. Improving the efficacy of hormonal therapy in MCF-7 breast cancer cells grown in the presence of IGF-I by targeting the MAPK/MEK and JAK/STAT cell survival signaling pathways. [D] . Welborn, April Eve. 2007

机译：通过靶向MAPK / MEK和JAK / STAT细胞存活信号通路，改善激素治疗在IGF-1存在下生长的MCF-7乳腺癌细胞中的功效。
6. Intratumoral Administration of Holmium-166 Acetylacetonate Microspheres: Antitumor Efficacy and Feasibility of Multimodality Imaging in Renal Cancer [O] . Wouter Bult, Stephanie G. C. Kroeze, Mattijs Elschot, 2010

机译：166乙酰丙酮Hol微球的肿瘤内给药：抗肿瘤功效和多模式成像在肾癌中的可行性。
7. Hydroxynaphthoquinone Metal Complexes as Antitumor Agents X: Synthesis, Structure, Spectroscopy and In Vitro Antitumor Activity of 3-Methyl-Phenylazo Lawsone Derivatives and Their Metal Complexes Against Human Breast Cancer Cell Line MCF-7 [O] . Gokhale, Nikhil, Padhye, Subhash, Newton, Chris, 2000

机译：羟基萘醌金属配合物作为抗肿瘤剂X：3-甲基苯基偶氮唑烷酮及其金属配合物对人乳腺癌细胞MCF-7的合成，结构，光谱和体外抗肿瘤活性

Antitumor Efficacy of Radioactive Holmium (~(166)Ho) Containing Silica Sol-gel Glass Granules on Osteosarcoma (MG-63) and Breast Cancer (MCF-7) Cells in Vitro

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