Intratumoral injection of radioactive holmium ( Ho-166) microspheres for treatment of oral squamous cell carcinoma in cats

van Nimwegen S. A.; Bakker R. C.; Kirpensteijn J.; van Es R. J. J.; Koole R.; Lam M. G. E. H.; Hesselink J. W.; Nijsen J. F. W.

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Intratumoral injection of radioactive holmium ( Ho-166) microspheres for treatment of oral squamous cell carcinoma in cats

机译：妥善注射放射性钬（HO-166）微球，用于治疗猫口腔鳞状细胞癌

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Background & AimsA microbrachytherapy was developed as treatment option for inoperable tumours by direct intratumoral injection of radioactive holmium-166 ( Ho-166) microspheres (MS). Ho-166 emits -radiation which potentially enables a high, ablative, radioactive-absorbed dose on the tumour tissue while sparing surrounding tissues.

机译：背景＆amp; 通过直接妥善注射放射性Holmium-166（HO-166）微球（MS），开发了AIMSA微生物放射治疗作为无法操作的肿瘤的治疗选择。 HO-166发射 - 在肿瘤组织上施加高，烧蚀的放射性吸收剂量，同时施加周围组织。

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来源
《Veterinary and Comparative Oncology》 |2018年第1期|共11页
作者
van Nimwegen S. A.; Bakker R. C.; Kirpensteijn J.; van Es R. J. J.; Koole R.; Lam M. G. E. H.; Hesselink J. W.; Nijsen J. F. W.;
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作者单位

Univ Utrecht Dept Clin Sci Compan Anim Fac Vet Med POB 80154 NL-3508 TD Utrecht Netherlands;

Univ Med Ctr Utrecht Dept Radiol &

Nucl Med Utrecht Netherlands;

Univ Utrecht Dept Clin Sci Compan Anim Fac Vet Med POB 80154 NL-3508 TD Utrecht Netherlands;

UMC Utrecht Canc Ctr Dept Head &

Neck Surg Oncol Utrecht Netherlands;

Univ Med Ctr Utrecht Dept Oral &

Maxillofacial Surg Utrecht Netherlands;

Univ Med Ctr Utrecht Dept Radiol &

Nucl Med Utrecht Netherlands;

Univ Utrecht Dept Clin Sci Compan Anim Fac Vet Med POB 80154 NL-3508 TD Utrecht Netherlands;

Univ Med Ctr Utrecht Dept Radiol &

Nucl Med Utrecht Netherlands;

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原文格式 PDF
正文语种 eng
中图分类动物医学（兽医学）;
关键词
head and neck; brachytherapy; holmium; tongue; feline; translational model; radionuclide; tumour;

机译：头部和颈部;近距离放射治疗;钬;舌头;猫科学;翻译模型;放射性核素;肿瘤;

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专利

1. Intratumoral injection of radioactive holmium ( Ho-166) microspheres for treatment of oral squamous cell carcinoma in cats [J] . van Nimwegen S. A., Bakker R. C., Kirpensteijn J., Veterinary and Comparative Oncology . 2018,第1期

机译：妥善注射放射性钬（HO-166）微球，用于治疗猫口腔鳞状细胞癌
2. Sequential injection of radioactive nanosized colloids followed by indocyanine green for sentinel lymph node detection in oral squamous cell carcinoma: A proof of concept [J] . Digonnet Antoine, Barbieux Romain, Quiriny Marie, Oral oncology . 2018,第期

机译：排序注射放射性纳米粒子胶体，然后是口腔鳞状细胞癌的丁内蛋白淋巴结检测的吲哚菁绿：概念证明
3. Intratumoral c-Met expression is associated with vascular endothelial growth factor C expression, lymphangiogenesis, and lymph node metastasis in oral squamous cell carcinoma: implications for use as a prognostic marker. [J] . Zhao D, Wang SH, Feng Y, Human Pathology . 2011,第10期

机译：肿瘤内c-Met表达与口腔鳞状细胞癌中的血管内皮生长因子C表达，淋巴管生成和淋巴结转移有关：用作预后标志物的意义。
4. TREATMENT OF ORAL SQUAMOUS CELL CARCINOMA IN AN ATLANTIC BOTTLENOSE DOLPHIN (Tursiops truncatus) [C] . Carolyn J. McKinnie, Samuel R. Dover, Gregory Ogilvie, Annual Conference of the International Association for Aquatic Animal Medicine . 2001

机译：大西洋瓶颈海豚口腔鳞状细胞癌（Tursiops truncatus）治疗
5. Histone demethylase JMJD6 enhances cancer stem cell phenotype in oral squamous cell carcinoma cells [D] . Lee, Chang-Ryul. 2014

机译：组蛋白脱甲基酶JMJD6增强口腔鳞状细胞癌细胞中的癌症干细胞表型
6. Intratumoral injection of radioactive holmium-166 microspheres in recurrent head and neck squamous cell carcinoma: preliminary results of first use [O] . Robbert C. Bakker, Robert J.J. van Es, Antoine J.W.P. Rosenberg, -1

机译：瘤内注射放射性166166微球治疗复发性头颈部鳞状细胞癌：首次使用的初步结果
7. EFFECT OF INTRATUMORAL INJECTION OF DOXORUBICIN IN THE TREATMENT OF INDUCED ORAL SQUAMOUS CELL CARCINOMA (EXPERIMENTAL STUDY) [O] . Marwa M. Essawy, Sahar M. El-Sheikh, Hanaa S. Raslan 2017

机译：腹腔内注射多柔比蛋白在诱导口腔鳞状细胞癌治疗中的影响（实验研究）

Intratumoral injection of radioactive holmium ( Ho-166) microspheres for treatment of oral squamous cell carcinoma in cats

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