The study of physical-chemical stability of the tablets of acetylsalicylfc acid and ascorbic acid

摘要

From analysis of the obtained data, results that the realized tablets, subdued of the degradation process, suffer a decomposition of 1.3-2.4% of the acetylsalicylic acid and 0.14-1.03% of the ascorbic acid in 21 days. Analyzing the influence of temperature concerning tablets, be seen that in absence of humidity, stand out a decomposition of 0.6-0.9% of the acetylsalicylic acid and 0.06-0.25% of the ascorbic acid. The capacity of formation of the kelatocompounds of EDTA - Na_2 leads to a good stability of ascorbic acid in the tabtets.