SYNTHESIS OF CERTAIN C-5 SUBSTITUTED DERIVATIVES OF 2',3'-DIDEOXY-URIDINE

机译：某些C-5取代的2'，3'-去氧尿苷的衍生物的合成

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The preparation of the 5-(3-hydroxyprapynyl)-2',3'-dideoxy-uridine, respectively 5-(3-hydroxypropyl)- 2',3'-dideoxy-uridine have been achieved in good yield. The synthesis involve the formation of a key intermediary 5'-O-acetyl-2',3'-dideoxy-uridine and it was obtained in three steps starting from the uridine.

机译：已经以良好的产率制备了5-（3-羟丙基吡啶）-2′，3′-二脱氧尿苷，分别制备了5-（3-羟丙基）-2′，3′-二脱氧尿苷。合成涉及关键的中间5'-O-乙酰基-2'，3'-二脱氧尿苷的形成，它是从尿苷开始的三个步骤中获得的。

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来源
《12th Romanian International Conference on Chemistry and Chemical Engineering Sep 13-15, 2001 Bucharest, Romania》|2001年|p.407-410|共4页
会议地点 Bucharest(RO);Bucharest(RO)
作者
E. Sugeac; A. Ciurea; Z. Delbederi; C. Fossey; D. Laduree; A.M. Aubertin; A. Kirn;
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作者单位

C.E.R.M.N., U.F.R. of Pharmaceuticals Sciences, Caen, France;

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会议组织
原文格式 PDF
正文语种 eng
中图分类化学工业;
关键词
2',3'-dideoxy-nucleosides; reverse transcriptase inhibitors; antiviral activity;

机译：2'，3'-双脱氧核苷;逆转录酶抑制剂;抗病毒活性;

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8. Synthesis of C-5 Substituted Tubercidin Derivatives. [R] . Bergstrom, D. E. 1980

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SYNTHESIS OF CERTAIN C-5 SUBSTITUTED DERIVATIVES OF 2',3'-DIDEOXY-URIDINE

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