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Screening methods and assays for use with transmembrane proteins, especially GPCRs
Screening methods and assays for use with transmembrane proteins, especially GPCRs
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机译:筛查方法和化验使用跨膜蛋白,特别是GPCRs
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摘要
The present invention provides methods and arrangements for screening membrane proteins. Arrangements are fused to a first fusion protein, including a membrane protein present at the border layer, such as the wall of a cell, liposome or vesicle, which is fused to one member of the binding pair, to another member of the binding pair. The binding pair can generate a detectable signal, comprising a second fusion protein comprising an intracellular ligand for the membrane protein. [Selection diagram] None
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