首页> 外国专利> Three-dimensional microenvironment structure for regulating cell behavior, three-dimensional surface for controlling cell behavior, array and manufacturing method of three-dimensional micro environment structure

Three-dimensional microenvironment structure for regulating cell behavior, three-dimensional surface for controlling cell behavior, array and manufacturing method of three-dimensional micro environment structure

机译:用于调节细胞行为的三维微环境结构,用于控制细胞行为的三维表面,三维微环境结构的阵列和制造方法

摘要

Problem to be solved: to provide a three-dimensional microenvironment structure capable of accurately adjusting cell behavior such as cell attachment, movement, growth and differentiation, a surface for controlling cell behavior, an array and a method of manufacturing a three-dimensional microenvironment structure.Nanofiber membraneA three-dimensional microenvironment structure that regulates two or more peptide motifs including two or more peptide motifs of P1 andThe peptide motifs of P1 and P2 areBound to two or more mutually different receptors on the cellGenerate a signal that controls the behavior of cellsThe P1 motif isIntegrin in α 5 β Includes a motif that combines withThe P2 motif isIntegrins above α 5 β As a motif binding to the coreceptor ofIntegrin in α 5 β Controlling the activity of the co receptor ofGenerate a signal that controls cell behaviorIt is a three-dimensional micro environment structure.No selection
机译:待解决的问题:提供一种能够精确调节细胞行为(例如细胞附着、移动、生长和分化)的三维微环境结构、用于控制细胞行为的表面、阵列和制造三维微环境结构的方法。纳米纤维膜调节两个或多个肽基序(包括P1的两个或多个肽基序)的三维微环境结构,P1和P2的肽基序与细胞上两个或多个相互不同的受体结合,产生控制细胞行为的信号。α5β中的P1基序isIntegrin包括与P2基序isIntegrin结合的基序以上α5β为一个基序,与α5β中的整合素辅受体结合,控制辅受体的活性,产生一个控制细胞行为的信号,这是一个三维微环境结构。没有选择

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