TRAJECTORY OPTIMIZATION USING DOSE ESTIMATION AND CONFLICT DETECTION

摘要

Systems and methods (200) for radiation treatment planning can include a computing system (150) determining (202) an estimate of radiation dose distribution within an anatomical region (302) of a patient, and determining (204) a cost matrix representing an objective function, using the estimate of radiation dose distribution. The computing system (150) can project (206) the cost matrix on each of a plurality of fluence planes. Each of the plurality of fluence planes can be associated with a corresponding gantry-couch orientation of a plurality of gantry-couch orientations of a medical linear accelerator. The computing system (150) can determine, using projections of the cost matrix on each of the plurality of fluence planes, a sequence of gantry- couch orientations among the plurality of gantry-couch orientations representing a treatment path