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STRONTIUM-82/RUBIDIUM-82 GENERATOR AND METHOD FOR ITS PREPARATION

机译:锶-82/铷-82发生器及其制备方法

摘要

FIELD: nuclear medicine.;SUBSTANCE: invention relates to techniques for nuclear medicine and can be used in the diagnosis of a number of cardiological and oncological diseases by positron emission tomography. The strontium-82/rubidium-82 generator includes a housing that is protected from ionizing radiation and contains a container with a protective insert, a generator column, and inlet and outlet tubes placed in the inner grooves of the insert. The internal space of the sealed container around the generator column with sealed covers with filters, inlet and outlet pipes is filled with heat-resistant epoxy resin. Sections of the inlet and outlet tubes above the sealed container are located in the upper cavity of the protective housing under the protective insert and are curved, and the protective insert is made of one-piece, solid lead. The generator manufacturing method includes filling the generator column with an ion-exchange material consisting of an inorganic sorbent of hydrated tin (IV) oxide in the form of a suspension in an aqueous ammonium hydroxide solution and containing tin hydroxide in the suspension.;EFFECT: increasing the efficiency and reliability of the strontium-82/rubidium-82 generator, the duration of its operation, a significant increase in its ion-exchange capacity relative to strontium, which reduces the breakthrough of strontium-82 and strontium-85 during its operation.;2 cl, 2 dwg
机译:领域:核医学。;物质:本发明涉及核医学技术,可通过正电子发射断层扫描用于许多心脏病和肿瘤疾病的诊断。锶-82/铷-82发生器包括一个防止电离辐射的外壳,并包含一个带有保护插件的容器、一个发生器柱,以及放置在插件内槽中的入口和出口管。发电机柱周围密封容器的内部空间(带有过滤器、入口和出口管的密封盖)填充耐热环氧树脂。密封容器上方的入口管和出口管段位于保护插件下方的保护壳的上腔中,并呈曲线状,保护插件由一体式实心铅制成。该发生器的制造方法包括用离子交换材料填充发生器柱,该离子交换材料由水合氧化锡(IV)的无机吸附剂组成,该无机吸附剂以悬浮液的形式存在于氢氧化铵水溶液中,且悬浮液中含有氢氧化锡。;影响:提高锶-82/铷-82发生器的效率和可靠性,延长其运行时间,显著增加其相对于锶的离子交换容量,从而减少锶-82和锶-85在运行期间的突破。;2 cl,2 dwg

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