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ANTIBIOTIC PEPTIDE WITH ANTIBIOTIC EFFECT ON VARIOUS MICROORGANISMS AND ANTIBIOTICS RESISTANT BACTERIA
ANTIBIOTIC PEPTIDE WITH ANTIBIOTIC EFFECT ON VARIOUS MICROORGANISMS AND ANTIBIOTICS RESISTANT BACTERIA
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机译:对各种微生物和抗生素耐药细菌具有抗菌作用的抗生素肽
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摘要
The present invention relates to an antibiotic peptide comprising a peptide comprising the amino acid sequence of SEQ ID NO: 1 and a cell penetrating peptide covalently linked to the end of the peptide, wherein the antibiotic peptide does not induce red blood cell hemolysis, and is It has low toxicity to normal cells and excellent antibiotic activity against various pathogenic microorganisms and antibiotic-resistant bacteria.
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机译:本发明涉及一种抗生素肽,其包含包含SEQ ID NO:1氨基酸序列的肽和共价连接至肽末端的细胞穿透肽,其中所述抗生素肽不会诱导红细胞溶血,它对正常细胞毒性低,对各种病原微生物和抗生素耐药细菌具有优良的抗菌活性。
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