NOVEL CYCLIC PEPTIDE COMPOUND, METHOD FOR PRODUCING SAME, ANTI-INFECTIVE AGENT, ANTIBIOTIC-CONTAINING FRACTION, ANTIBIOTIC, METHOD FOR PRODUCING ANTIBIOTIC, ANTIBIOTIC-PRODUCING MICROORGANISM, AND ANTIBIOTIC PRODUCED BY SAME

摘要

Provided are: a novel compound having a structuredifferent from that of existing drugs; a novel microorganismcapable of producing the novel compound; and further; a novelcompound effective to a multiple-drug-resistant bacterium. Toprovide a novel compound having a high therapeutic effect whichcan be expected to have a low hurdle for practical realizationby selecting an intended compound from many candidate compoundsbased not only on an antibacterial activity but also onevaluation including a therapeutic effect, a cyclic peptidecompound shown by the following formula (1) or apharmaceutically allowable salt thereof and a microorganismwith Accession No. NITE BP-870 or a microorganism mutatednaturally or artificially therefrom are provided.(In the formula (1) , R1 represents an acyl group having7 , 8, or 9 carbon atoms and optionally containing a substituentgroup; R2 represents a methyl group or a hydrogen atom; and R3represents an ethyl group or a methyl group.)92