CATECHOLAMINE CONCENTRATIONS IN A BLOOD SAMPLE AND ARTERIAL HYPERTENSION STATUS IN A SUBJECT FOR A DIFFERENTIAL DIAGNOSIS OF NEURODEGENERATIVE DISEASES INCLUDING ALZHEIMER'S DISEASE

摘要

The invention has for object an in vitro method for performing a differential diagnosis of neurodegenerative diseases selected from early stage of Alzheimer's disease, advanced stage of Alzheimer's disease, mental depression, dementia with Lewy bodies, frontotemporal dementia, and/or vascular dementia; said method being performed in a subject presenting signs of dementia and comprising the steps of (a) determining at least five criteria of said subject, said at least five criteria comprising the age of said subject, a score of said subject to a questionnaire adapted for screening cognitive function, a dopamine, adrenaline and noradrenaline concentration in a blood sample of said subject, (b) comparing said noradrenaline concentration to a predetermined threshold, (c) calculating one global note in relation with each neurodegenerative disease and (d) determining whether said subject suffers from one or more neurodegenerative diseases.