Method for enhancing generation or increasing productivity of exosomes and/or extracellular vesicles

摘要

The present invention relates to animal-derived cells using retinoic acid, silymarin, IL-17A, IL-17F, IL-22, IL-1β, poly I:C, PPARβ/δ antagonists or a combination thereof, preferably retinoic acid, IL- 17A and poly I: It provides a method of promoting or enhancing productivity of exosomes and/or extracellular vesicles, comprising the step of culturing in a medium containing at least one selected from the group consisting of: The present invention can improve the productivity of exosomes and/or extracellular vesicles secreted or released per cell (or cell culture medium), and thus can be used commercially and/or clinically usefully for exosomes and/or extracellular The endoplasmic reticulum can be produced economically and efficiently in high yield, and in particular, there is an advantage in that exosomes and/or extracellular vesicles can be produced in large quantities compared to the conventional method.