首页> 外国专利> BIOMARKER COMPOSITION FOR PREDICTING PROGNOSIS OF BRAIN DISEASE CAUSED BY MICROPLASTIC EXPOSURE AND METHOD FOR PREDICTING PROGNOSIS USING SAME

BIOMARKER COMPOSITION FOR PREDICTING PROGNOSIS OF BRAIN DISEASE CAUSED BY MICROPLASTIC EXPOSURE AND METHOD FOR PREDICTING PROGNOSIS USING SAME

机译:用于预测微塑性暴露引起的脑病预后的生物标志物组合物及其使用方法预测预测

摘要

The present invention relates to: a biomarker composition for predicting the prognosis of brain disease caused by microplastic exposure; and a use thereof. More particularly, it was confirmed that polyethylene microspheres (PS) in a mouse animal model orally administered with the PS penetrate brain tissue to change the level of metabolites inside the brain tissue and the diversity of intestinal microorganisms, thereby causing brain disease, and thus the present invention is intended to provide a biomarker composition for predicting the prognosis of brain disease caused by microplastic exposure, and a method for predicting the prognosis of brain disease using same.
机译:本发明涉及:用于预测微塑性暴露引起的脑疾病预后的生物标志物组合物; 和使用的用途。 更具体地,证实了与PS口服脑组织口服给药的小鼠动物模型中的聚乙烯微球(PS)以改变脑组织内部代谢物水平和肠道微生物的多样性,从而引起脑疾病,从而造成脑疾病 本发明旨在提供一种用于预测微塑性暴露引起的脑疾病预后的生物标志物组合物,以及预测使用该脑疾病预后的方法。

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