MITOCHONDRIAL ACTIVITY INHIBITORS TARGETING TUMORAL METABOLISM

摘要

The invention relates to compounds of formula (I) as follows: (I) wherein X1 and X2, identical or different, are NR5 or a sulfur atom, Y is a group (C1-C10)alkanediyl, Ar1 and Ar2, identical or different, are an aryl group optionally substituted by one or several groups selected from a halogen atom, a (C1-C6) alkyl, —OR1, —NR1R2 and —COOR3′ with R1 and R2, independently of each other, are a hydrogen atom, a (C-1-C6) alkyl group or a —COR3 group, R3 and R4′ independently of each other, are a hydrogen atom or a (C1-C6) alkyl group, and R5 is a hydrogen atom or a (C1-C6)alkyl group, or a pharmaceutically acceptable salt and/or solvate thereof, in particular for use in cancer treatment.;