MITOCHONDRIAL ACTIVITY INHIBITORS TARGETING TUMORAL METABOLISM

摘要

The invention relates to compounds of formula (I) as follows: (I) wherein X¹ and X², identical or different, are NR⁵or a sulfur atom, Y is a group (C₁-C₁₀)alkanediyl, Ar¹ and Ar², identical or different, are an aryl group optionally substituted by one or several groups selected from a halogen atom, a (C₁-C₆) alkyl, -OR¹, -NR¹R² and -COOR^3, with R¹ and R², independently of each other, are a hydrogen atom, a (C-₁-C₆₎ alkyl group or a -COR³ group, R³ and R^4, independently of each other, are a hydrogen atom or a (C₁-C₆) alkyl group, and R⁵ is a hydrogen atom or a (C₁-C₆)alkyl group, or a pharmaceutically acceptable salt and/or solvate thereof, in particular for use in cancer treatment.