Methods of Using Anti-HLA-G Antibodies, Compositions Containing Anti-HLA-G Antibodies, and Anti-HLA-G Antibodies

摘要

An antibody that selectively binds to HLA-G, and a composition comprising the antibody are provided herein. Methods using antibodies such as therapeutic and diagnostic methods are also provided. In some embodiments, the antibody binds to human HLA-G. In some embodiments, the antibody comprises at least one CDR sequence as defined by the consensus sequences provided in the present disclosure. In some embodiments, the antibody comprises an exemplary CDR, VE or VL sequence provided in the present disclosure, or one or more of these variants. In some embodiments, the variant is a variant having one or more conservative amino acid substitutions.