HISTONE DEACETYLASE 6 INHIBITION FOR ENHANCING T-CELL FUNCTION DURING ANTI-TUMOR RESPONSE AND TUMOR-PEPTIDE VACCINATION

摘要

Disclosed are methods whereby an effective amount of a HDAC6 inhibitor is used to activate a subjects T-cell response to tumor or tumor vaccine. Methods of using HDAC6 inhibitors to increase a subjects anti-tumor immune response, alone or in conjunction with other tumor treatments, are also disclosed.