The present disclosure provides a method of fabricating an organic light-emitting diode (OLED) display panel and an organic light-emitting diode (OLED) display panel. The OLED display panel includes a substrate; a driving circuit layer formed on the substrate; a pixel defining layer; and a light emitting functional layer, which are stacked. Protrusions are provided on a surface of the pixel defining layer away from the driving circuit layer in at least one of a plurality of pixel defining regions, and the light emitting functional layer is formed on the pixel defining layer and covers the sub-pixel regions. By forming the protrusions, a lateral transmission path of charges between adjacent sub-pixels is increased, resulting in a reduction in light leakage.
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