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DESIGN, SYNTHESIS OF NOVEL OXYINDOLE INHIBITORS OF DENV RNA DEPENDENT RNA POLYMERASE

机译:Denv RNA依赖性RNA聚合酶新型氧吲哚吲哚抑制剂的设计

摘要

The present invention is drawn to novel compounds of formula I, II and III, including any conformational isomeric form, salts and solvates for inhibition of DENV RNA dependent and RNA polymerase. The present invention also discloses a process of synthesis of the compounds, compositions comprising the said compounds and use of the compounds and treatment comprising the compounds of the present invention.
机译:将本发明的式I,II和III化合物抽取,包括任何构象异构形式,盐和溶剂化物,用于抑制DENV RNA依赖性和RNA聚合酶。 本发明还公开了化合物的合成方法,包含所述化合物的组合物和使用本发明化合物的化合物和处理的用途。

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