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MICROBEADS FOR TAGLESS ENCODED CHEMICAL LIBRARY SCREENING

机译:无标记编码化学文库筛选的Microbeads

摘要

Disclosed is an encoded chemical library microbead, which microbead has immobilized thereon and/or therein: (i) an encoding tag; and (ii) a target assay system reporter moiety, wherein the reporter moiety exists in a first state in the absence of activity against the target and in a second state in the presence of said activity, and wherein said microbead further comprises a clonal population of one or more chemical structure(s) releasably linked thereto and encoded by said tag.
机译:公开了一种编码的化学文库微珠,微珠在其上固定和/或其中:(i)编码标签; (ii)一种目标测定系统报告部部分,其中报告部分在不存在对靶的活性和在所述活性存在下的第二状态的第一状态下存在,并且所述微生物还包含克隆人群 一种或多种化学结构可释放地连接到其上并由所述标签编码。

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