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Compound inhibiting YAP-TEAD interaction and pharmaceutical composition for treating or preventing cancer comprising the same as an active ingredient
Compound inhibiting YAP-TEAD interaction and pharmaceutical composition for treating or preventing cancer comprising the same as an active ingredient
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机译:化合物抑制Yap-Tead相互作用和药物组合物,用于治疗或预防包含与活性成分相同的癌症
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摘要
The present invention relates to a compound that inhibits YAP (Yes associated protein)-TEAD (transcriptional enhancer associate domain) binding, a prodrug thereof, a hydrate thereof, a solvate thereof or a pharmaceutically acceptable salt thereof, and a composition containing the same as an active ingredient In this regard, the compound according to the present invention may act as an inhibitor capable of directly inhibiting YAP-TEAD binding in the hippo pathway, which plays a key role in the development of cancer.
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