首页> 外国专利> Compound inhibiting YAP-TEAD interaction and pharmaceutical composition for treating or preventing cancer comprising the same as an active ingredient

Compound inhibiting YAP-TEAD interaction and pharmaceutical composition for treating or preventing cancer comprising the same as an active ingredient

机译:化合物抑制Yap-Tead相互作用和药物组合物,用于治疗或预防包含与活性成分相同的癌症

摘要

The present invention relates to a compound that inhibits YAP (Yes associated protein)-TEAD (transcriptional enhancer associate domain) binding, a prodrug thereof, a hydrate thereof, a solvate thereof or a pharmaceutically acceptable salt thereof, and a composition containing the same as an active ingredient In this regard, the compound according to the present invention may act as an inhibitor capable of directly inhibiting YAP-TEAD binding in the hippo pathway, which plays a key role in the development of cancer.
机译:本发明涉及一种抑制YAP(是相关蛋白质)-TEAD(转录增强剂助剂域)结合,其前药,其水合物,其水合物或其药学上可接受的盐的化合物的化合物,其溶剂质及其药学上可接受的盐,以及含有相同的组合物 在这方面的活性成分中,根据本发明的化合物可以用作能够直接抑制河马途径中的粘连结合的抑制剂,这在癌症的发展中起关键作用。

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