Peripheral blood biomarkers for evaluation of antitumor immunity by radiotherapy

摘要

Provide a peripheral blood biomarker for evaluating antitumor immunity by radiotherapy.The present invention provides a method of making the composition of a cell subpopulation in a sample obtained from a subject an indicator of immune activation by radiation therapy in a subject.CD4 + T cell subpopulations correlated with dendritic cell stimulation in antitumor immune responses, or by comparing the amount of dendritic cell subpopulations correlated with dendritic cell stimulation in antitumor immune responses to reference The presence or absence of immunoactivation by radiation therapy occurring in the subject can be determined.