Asymmetric siRNA suppresses expression of male type hair loss target genes

摘要

An asymmetric siRNA that suppresses the expression of a male-type hair loss target gene and a use thereof are provided. Kind Code: A1 Suppression of the expression of SRD5A1 (3-oxo-5-alpha-steroid 4-dehydrogenase 1) gene, SRD5A2 (3-oxo-5-alpha-steroid 4-dehydrogenase 2) gene or AR (Adrogen receptor) gene. And a composition for preventing or treating hair loss comprising the asymmetric siRNA.