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Compositions and methods for the production of pyruvic acid and related products using dynamic metabolic control
Compositions and methods for the production of pyruvic acid and related products using dynamic metabolic control
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机译:使用动态代谢控制生产丙酮酸和相关产品的组合物和方法
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摘要
The present disclosure is related to genetically engineered microbial strains and related bioprocesses for the production of pyruvate and related products. Specifically, the use of dynamically controlled synthetic metabolic valves to reduce the activity of enzymes known to contribute to pyruvate synthesis, leads to increased pyruvate production in a two-stage process rather than a decrease in production.
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