USE OF E. COLI STRAINS EXPRESSING HIGH LEVEL OF ALPHA-GAL TO MODULATE IMMUNITY AND PROVIDE PROTECTION AGAINST INFECTIOUS DISEASES IN ANIMALS

摘要

The present invention concerns an E. coli strains expressing high level of α-Gal, in particular selected in the group consisting of E. coli Nissle 1917 strain, E.coli O111 strain, E. coli O86: B7 strain, and mixture thereof, as a probiotic and/or feed additive and/or oral vaccine in a non-human animal, in particular fish and poultry, to prevent and/or reduce an infectious disease caused by a pathogen expressing α-Gal on its surface.