The specification generally relates to Formula I: [Formula I] to compounds of and pharmaceutically acceptable salts thereof, wherein R 1 , R 2 , R 3 , R 4 , R 6 , R 7 , R 8 , linkers, A, G, D and E are as defined herein have any meaning. The specification also relates to the use of said compounds and pharmaceutically acceptable salts thereof in a method of treatment of the human or animal body, for example in the prevention or treatment of cancer. The specification also relates to the processes and intermediate compounds involved in the preparation of such compounds, and to pharmaceutical compositions containing them.
展开▼
