Complex composition for differentiation of periodontal ligament cells to cementoblast

摘要

The present invention is a TGF-β (transforming growth factor-beta) receptor ALK (activin receptor-like kinase) 5 inhibitor, BMP-7 (bone morphogenetic protein-7), and the differentiation of periodontal ligament cells containing ascorbic acid into cerebroblasts It relates to a composition for induction. According to the present invention, by isolating periodontal ligament cells from human adult periodontal ligament tissue and treating them with a transforming growth factor-beta (TGF-β) receptor activin receptor-like kinase (ALK) 5 inhibitor, BMP-7 and ascorbic acid , periodontal ligament cells can be differentiated significantly and effectively compared to the existing differentiation method into chorionic cells, which are the target cells. can be used to discover