Composition for differentiation of periodontal ligament cells to Cementoblast

摘要

The present invention relates to a composition, a medium, a kit, and a method for inducing differentiation of periodontal ligament cells into blastocysts comprising a transforming growth factor-beta (TLG-beta) receptor activin receptor-like kinase (ALK) 5 inhibitor. It is about. According to the present invention, by separating the periodontal ligament cells from human adult periodontal ligament cells and treating them with TGF-β receptor ALK5 inhibitors, the periodontal ligament cells can be effectively induced into differentiation into the target cells, the chalk cells, By obtaining the chalk cells necessary for regeneration, it can be used to study chalk formation and regeneration and to discover surface expression markers specific thereto.