首页> 外国专利> Camellia nitidissima Chi extracted theaflavin medicament for resisting novel coronavirus and preparation method and application thereof

Camellia nitidissima Chi extracted theaflavin medicament for resisting novel coronavirus and preparation method and application thereof

机译:Camellia Nitissima Chi提取了硫蛋白药物,用于抵抗新型冠状病毒及其制备方法和应用

摘要

Novel coronavirus medicament comprising: 20-60 parts theaflavin-3-monogallate extracted from Camellia nitidissima (golden camellia); 20-60 parts theaflavin-3,3’-digallate extracted from Camellia nitidissima; 3-8 parts hyaluronic acid; 8-20 parts nicotinamide; 15-30 parts ceramide; 3-10 parts pyruvate; 12-30 parts sodium pyruvate; 3-8 parts polyhaxemethyleneguanidine; 5-15 parts Tween; 150-500 parts glycerol; and 15-35 parts p-hydroxybenzoic ester. Also disclosed is a method of extracting theaflavins from Camellia nitidissima comprising: washing, drying, crushing, and sieving Camellia nitidissima to obtain powder; adding anhydrous ethyl acetate to extract; evaporating and washing with chloroform and drying (vacuum, 30-80 °C) to obtain crude theaflavin. Theaflavin-3-monogallate and theaflavin-3,3’-digallate are obtained from crude theaflavin by countercurrent chromatography. The medicament is obtained by mixing the extracts with hyaluronic acid, nicotinamide, ceramide, pyruvic acid, sodium pyruvate, polyhexamethylguanidine, Tween, glycerol, and p-hydroxybenzoate to obtain a powder, before ethanol is added and the powder dissolved .The medicament may be a spray.
机译:新型冠状病毒药物,包括:20-60份从山茶花(Golden Camellia)提取的秋草-3-单金属酸盐; 20-60份Theaflawin-3,3'--3- inallate从Camellia Nitissima提取; 3-8份透明质酸;烟酰胺8-20份; 15-30份神经酰胺; 3-10份丙酮酸; 12-30份丙酮酸钠; 3-8份多亚甲基甲基胍; 5-15份吐温; 150-500份甘油;和15-35份对羟基苯甲酸酯。还公开了一种从Camellia Nitissima提取秋季霉素的方法,包括:洗涤,干燥,破碎和筛分山茶花Nitissima以获得粉末;加入无水乙酸乙酯以提取物;用氯仿和干燥(真空,30-80℃)蒸发和洗涤,得到粗产物。 Theaflawin-3-单甘露酸酯和Theaflawin-3,3'-次千酸盐由逆流色谱法从粗素霉素获得。通过将具有透明质酸,烟酰胺,神经酰胺,丙酮酸,丙酮酸钠,聚己烷基甲烷,吐温,甘油和对羟基苯甲酸酯混合来获得的药物获得,得到粉末,在加入乙醇之前,粉末溶解。药物可能是喷雾。

著录项

  • 公开/公告号GB2594793A

    专利类型

  • 公开/公告日2021-11-10

    原文格式PDF

  • 申请/专利权人 SHAOGUAN UNIVERSITY;

    申请/专利号GB20210004084

  • 发明设计人 JINSHENG CHENG;WEIHONG WAN;

    申请日2021-03-24

  • 分类号A61K31/353;A61K36/82;A61P31/16;

  • 国家 GB

  • 入库时间 2022-08-24 22:28:41

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