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Connexin45 inhibitors for therapy

机译:Connexin45治疗抑制剂

摘要

Problem to be solved: to provide a composition for treating, preventing, preventing or preventing the progression of cardiac dysfunction associated with myocardial infarction, cardiac dysfunction characterized by abnormal conduction and other cardiac conditions.The composition of the composition comprising one or more inhibitors of connexin 45 (Cx45), preferably an inhibitor of Cx45, is a small molecule, protein or nucleic acid composition, more preferably an inhibitor of Cx45, is a nucleic acid molecule that contains a DNA sequence encoding the RNA molecule.It also provides the use of inhibitors of Cx45 in the manufacture of pharmaceuticals to prevent and prevent myocardial infarction related complications in the subject, or to inhibit its progression or reduce the possibility of its occurrence.Selection diagram
机译:要解决的问题:提供一种用于治疗,预防,预防或预防与心肌梗死相关的心脏功能障碍进展的组合物,其特征在于异常传导和其他心脏条件。包含一种或多种Connexin抑制剂的组合物的组合物 45(CX45),优选CX45的抑制剂是小分子,蛋白质或核酸组合物,更优选CX45的抑制剂,是含有编码RNA分子的DNA序列的核酸分子。还提供了使用 CX45的抑制剂在制造药物中,以预防和预防受试者中的心肌梗死相关并发症,或抑制其进展或减少其发生的可能性。选择图

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