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SELECTIVE INHIBITORS OF ALPHA2-CONTAINING ISOFORMS OF NA,K-ATPASE AND USE THEREOF FOR REDUCING INTRAOCULAR PRESSURE
SELECTIVE INHIBITORS OF ALPHA2-CONTAINING ISOFORMS OF NA,K-ATPASE AND USE THEREOF FOR REDUCING INTRAOCULAR PRESSURE
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机译:Na,K-ATP酶的含alpha2的同种型的选择性抑制剂及其用途,用于降低眼压
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摘要
The present invention relates to a pharmaceutical composition comprising as active ingredients a compound represented by general Formula I:;including any pharmaceutically acceptable salt, hydrate, solvate, enantiomer and diastereomer thereof, and any mixtures thereof,wherein:X and R are as herein defined andat least one ingredient selected from the group consisting of a prostaglandin analog, a β-blocker, an adrenergic agent, an α2-adrenergic receptor agonist, a miotic agent, a carbonic anhydrase inhibitor and a cholinergic agonist, anda pharmaceutically acceptable carrier.
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