X-RAY IMAGE SYNTHESIS FROM CT IMAGES FOR TRAINING NODULE DETECTION SYSTEMS

摘要

Systems and methods for generating synthesized medical images for training a machine learning based network are provided. An input medical image in a first modality is received. The input medical image comprises a nodule region for each of one or more nodules and a remaining region. The input medical image comprises an annotation for each of the one or more nodules. A synthesized medical image in a second modality is generated from the input medical image. The synthesized medical image comprises the annotation for each of the one or more nodules. A synthesized nodule image of each of the nodule regions and synthesized remaining image of the remaining region are generated in the second modality. It is determined whether each particular nodule of the one or more nodules is visible in the synthesized medical image based on at least one of the synthesized nodule image for the particular nodule and the synthesized remaining image. In response to determining that at least one nodule of the one or more nodules is not visible in the synthesized medical image, the annotation for the at least one not visible nodule is removed from the synthesized nodule image.