A teniposide injection with high dilution stability and preparation method thereof

摘要

A teniposide injection or powder injection contains teniposide, cyclodextrin, stabilizer and additive, wherein the mass ratio of teniposide to cyclodextrin is 1:(5-20). Compared with a commercially available teniposide injection (VUMON), the teniposide preparations of the present invention do not contain polyoxyethylated castor oil, benzoic acid and N, N-dimethylacetamide and is low in toxic and side effects; the adverse reaction of patients can be reduced; and the patient compliance is high.