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SECRETORY IMMUNOGLOBULIN A (SIGA)-BINDING NUCLEIC ACID MOLECULE, SENSOR FOR SIGA ANALYSIS, AND ANALYSIS METHOD FOR SIGA
SECRETORY IMMUNOGLOBULIN A (SIGA)-BINDING NUCLEIC ACID MOLECULE, SENSOR FOR SIGA ANALYSIS, AND ANALYSIS METHOD FOR SIGA
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机译：分泌物免疫球蛋白A（SIGA） - 粘合核酸分子，SIGA分析传感器，以及SIGA的分析方法
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摘要
The present invention provides a novel molecule that can be used for detection of sIgA. The sIgA-binding nucleic acid molecule of the present invention is characterized in that it binds to secretory immunoglobulin A (sIgA) with a dissociation constant of 37.7 nM or less, and preferably includes a polynucleotide consisting of any of base sequences of SEQ ID NOs: 1 to 12 or a partial sequence thereof, for example. According to the sIgA-binding nucleic acid molecule of the present invention, it is possible to detect sIgA in saliva.
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机译：本发明提供一种新型分子，可用于检测SIGA。 本发明的SIGA结合核酸分子的特征在于，它与分泌物免疫球蛋白A（SIGA）结合，所述解离常数为37.7nm或更小，并且优选包括由SEQ ID NOS的任何基本序列组成的多核苷酸： 例如，1至12或其部分序列。 根据本发明的SIGA结合核酸分子，可以检测唾液中的SIGA。
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