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TYPE 1 INTERFERON NEUTRALIZING FC-FUSION PROTEIN AND USE THEREOF
TYPE 1 INTERFERON NEUTRALIZING FC-FUSION PROTEIN AND USE THEREOF
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机译:类型1干扰素中和Fc-融合蛋白及其用途
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摘要
The present invention relates to a type 1 interferon neutralizing FC-fusion protein and a use thereof and, more specifically, to: a dimer-type polypeptide to which a monomer comprising an interferon receptor fragment or an antibody Fc fragment is bound; a preparation method there for; and a pharmaceutical composition comprising same. The type 1 interferon neutralizing FC-fusion protein of the present invention blocks binding between type 1 interferon and an interferon receptor, and has an excellent ability of inhibiting the signaling and biological activities of interferon, thereby enabling diseases mediated by a type 1 interferon to be effectively treated.
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