There is provided a patient tailored-installable negative pressure isolator that can be easily installed on a bed, etc., can provide an independent isolation space for each patient, and has a structure that can be flexibly deformed, depending on situations. The patient tailored-installable negative pressure isolator includes: a base configured to be disposed under the back of the head of a patient lying down; a fixed cover connected to the base, configured to cover the face of the patient, having an intake tube connected to a side thereof to suction air, being maintained at negative pressure, and having an opening formed toward the body of the patient; and a variable cover connected to the opening of the fixed cover, configured to stretch and contract along the body of the patient, configured to cover the patient, and having an internal negative pressure space communicating with the fixed cover.
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