PROTEIN DIAGNOSTIC BIOMARKER FOR SEVERE DRUG ERUPTION

摘要

To develop biomarkers for diagnosis of the pathology, exacerbation, and type of severe drug eruptions such as drug-induced hypersensitivity syndrome and Stevens-Johnson syndrome/toxic epidermal necrolysis. A test method for severe drug eruption that includes measuring the expression of at least one protein selected from the group consisting of stratifin, TNF receptor superfamily member 8 (CD30/TNFRSF8), interleukin-1 receptor antagonist (IL-1Ra), and TNF receptor superfamily member 6B (DcR3/TNFRSF6B) in a sample derived from a subject.