SYSTEM AND METHOD FOR DETERMINING DIFFERENTIAL PROTEIN EXPRESSION, DIAGNOSTIC BIOMARKER DISCOVERY SYSTEM AND METHOD OF USING THE SAME, AND PROTEIN BIOMARKERS AND THERAPEUTIC AND DIAGNOSTIC USES THEREOF

摘要

The present invention relates generally to systems and methods for determining differential protein expression, and diagnostic discovery systems and methods that utilize the same. In particular, the present invention relates to a system and method of obtaining and analyzing protein profiles to determine protein patterns associated with clinical parameters and manifestations of disease and to discover specific biomarkers that are characteristic of diseases such as cancer. The present invention further relates to the identification of potential molecular targets for diagnostic applications and/or therapeutic intervention.