LONG-TERM RE-ABSORBABLE SUBCUTANEOUS IMPLANT WITH CONTROLED PRE-CONCENTRATED PHARMACOLOGICALLY ACTIVE POLYMER SUBSTANCE RELEASE FOR TREATING ENDOMETRIOSIS

摘要

The present invention is aimed at the medical sector and comprises a biodegradable implant of gestrinone in a polymeric matrix. The implant is inserted subdermally and has a continuous release of the asset for an extended period of time. This release aims to guarantee an efficient, constant and prolonged serum level of the drug for the treatment of endometriosis. The implant of the present invention may have only gestrinone in its constitution, but it is preferably formed by particles of gestrinone dispersed homogeneously in a bioerodible and bioabsorbable polymeric matrix. This polymeric matrix can be formed by a polymer or a mixture of polymers. The implants can have any size, shape or structure that facilitates their manufacture and insertion, however, to obtain a more constant and uniform release of the asset, it is necessary to use geometric shapes that maintain their surface area over time.