首页> 外国专利> COMPOSITIONS AND METHODS FOR TREATING AND/OR PREVENTING CELL OR TISSUE NECROSIS SPECIFICALLY TARGETING CATHEPSIN C AND/OR CELA1 AND/OR CELA3A AND/OR STRUCTURALLY RELATED ENZYMES THERETO

COMPOSITIONS AND METHODS FOR TREATING AND/OR PREVENTING CELL OR TISSUE NECROSIS SPECIFICALLY TARGETING CATHEPSIN C AND/OR CELA1 AND/OR CELA3A AND/OR STRUCTURALLY RELATED ENZYMES THERETO

机译：用于治疗和/或预防细胞或组织坏死特异性靶向组织蛋白酶C和/或CELA1和/或CELA3A和/或结构相关酶的细胞或组织坏死的组合物和方法

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摘要

Inhibitor compounds and agents of Cathepsin C, CELA1, CELA3A and/or structurally related molecules thereto, compositions comprising same and uses thereof in the inhibition and/or prevention of cell and/or tissue necrosis is described. Various applications for the described compounds, and combination therapies are described as well.

机译：描述了抑制剂化合物和组合物化合物和/或结构上相关分子的组合物，其组合物包含其在抑制和/或预防细胞和/或组织坏死中的组合物。还描述了所描述的化合物和组合疗法的各种应用。

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公开/公告号US2021309620A1

专利类型
公开/公告日2021-10-07

原文格式PDF
申请/专利权人 ELA PHARMA LTD;
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申请/专利号US202117201201
发明设计人 ILANA NATHAN;BORIS KHALFIN;
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申请日2021-03-15
分类号C07D265/22;A61K31/4178;A61K31/426;A61K31/454;C07D277/42;C12N15/113;A61K31;A61K31/496;A61K31/415;C07D405/06;C07D277/56;A61K31/4439;C07D233/44;C07D417/12;A61K31/4196;A61K31/4045;A61P25;A61K31/167;A61K31/428;A61K31/536;A61K45/06;C07C233/24;C07D233/48;C07D275/06;C12N5/077;
国家 US
入库时间 2022-08-24 21:30:39

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