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mTOR Novel compounds as mTOR inhibitor and uses thereof

机译:MTOR新化合物作为MTOR抑制剂及其用途

摘要

The present invention relates to a novel compound as an mTOR inhibitor and its use, and more particularly, to a novel compound represented by Formula 1 exhibiting mTOR inhibitory activity, and a pharmaceutical composition for preventing or treating mTOR pathway-related brain disease comprising the same as an active ingredient is about The compound represented by Formula 1 according to the present invention has excellent mTOR inhibitory effect and excellent blood-brain barrier permeability, so it can be very usefully utilized for the prevention or development of therapeutic agents for mTOR pathway-related brain diseases.
机译:本发明涉及一种作为MTOR抑制剂的新化合物及其使用,更具体地,涉及一种表现出MTOR抑制活性的式1表示的新化合物,以及用于预防或治疗包含相同的MTOR途径相关脑疾病的药物组合物 作为活性成分,根据本发明的式1表示的化合物具有优异的MTOR抑制作用和优异的血脑屏障渗透性,因此可以非常有用用于预防或开发MTOR途径相关的治疗剂 脑病。

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