首页> 外国专利> Screening Methods for Ameliorating or Prophylactic Drugs for Retinal and / or Photoreceptive Symptoms and Substances for Ameliorating or Preventing Retina and / or Photoreceptive Symptoms

Screening Methods for Ameliorating or Prophylactic Drugs for Retinal and / or Photoreceptive Symptoms and Substances for Ameliorating or Preventing Retina and / or Photoreceptive Symptoms

机译:用于改善或预防性药物的筛选方法,用于视网膜和/或光接收症状和改善或预防视网膜和/或光接收症状的物质

摘要

A drug for improving or preventing symptoms related to retina and / or photoreception, which contains a substance that maintains or enhances the phosphorylation state of Unc119 as an active ingredient, a step of selecting a substance that inhibits calcinulin, or activation of casein kinase 2. A method for screening a substance for improving or preventing symptoms related to the retina and / or photoreception, including a step of selecting a substance to be converted, and a substance for maintaining or enhancing the phosphorylated state of Unc119 are contained as active ingredients. Provided are a retinal degeneration inhibitor and a retinal protective agent.
机译:一种药物,用于改善或预防与视网膜和/或光接收有关的症状,其含有保持或增强UNC119作为活性成分的磷酸化状态的物质,是选择抑制钙素的物质,或激活酪蛋白激酶2的步骤。 一种用于筛选用于改善或防止与视网膜和/或光接收有关的症状的物质的方法,包括选择要转化的物质的步骤,以及用于维持或增强UNC119的磷酸化状态的物质作为活性成分。 提供了视网膜变性抑制剂和视网膜保护剂。

著录项

  • 公开/公告号JPWO2020080275A1

    专利类型

  • 公开/公告日2021-09-30

    原文格式PDF

  • 申请/专利权人 国立大学法人大阪大学;

    申请/专利号JP20200553143

  • 发明设计人 古川 貴久;茶屋 太郎;

    申请日2019-10-11

  • 分类号A61K45;A61K38/13;A61K31/706;A61P27/02;A61P43;A61P25/06;A61P25/20;A61P25/08;A61P25/18;A61P9;C12Q1/48;G01N33/68;G01N33/50;G01N33/15;

  • 国家 JP

  • 入库时间 2022-08-24 21:23:33

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