首页> 外国专利> MEDICINE FOR IMPROVING OR PREVENTING SYMPTOMS RELATED TO RETINA AND/OR PHOTORECEPTION AND METHOD FOR SCREENING SUBSTANCE IMPROVING OR PREVENTING SYMPTOMS RELATED TO RETINA AND/OR PHOTORECEPTION

MEDICINE FOR IMPROVING OR PREVENTING SYMPTOMS RELATED TO RETINA AND/OR PHOTORECEPTION AND METHOD FOR SCREENING SUBSTANCE IMPROVING OR PREVENTING SYMPTOMS RELATED TO RETINA AND/OR PHOTORECEPTION

机译:用于改善或预防与视网膜和/或光照相症状的症状和用于筛选物质的方法,改善或预防与视网膜和/或光接收有关的症状

摘要

The present invention provides a medicament for improving or preventing a symptom relating to a retina and/or light reception, the medicament comprising, as an active ingredient, a substance capable of maintaining or enhancing the phosphorylation state of Unc119; a method for screening for a substance capable of improving or preventing a symptom relating to a retina and/or light reception, the method comprising the step of selecting a substance capable of inhibiting calcineurin, or selecting a substance capable of activating casein kinase 2; and an agent for inhibiting retinal degeneration and an agent for protecting a retina, the agents each comprising, as an active ingredient, a substance capable of maintaining or enhancing the phosphorylation state of Unc119.
机译:本发明提供了一种用于改善或预防与视网膜和/或光接收有关的症状的药物,其包含作为活性成分的药物,能够维持或增强UNC119的磷酸化状态的物质; 一种筛选能够改善或预防与视网膜和/或光接收有关的症状的物质的方法,该方法包括选择能够抑制钙蛋白素的物质的步骤,或选择能够激活酪蛋白激酶2的物质; 和用于抑制视网膜退化的药剂和用于保护视网膜的试剂,所述试剂各自包含作为活性成分,其能够维持或增强UNC119的磷酸化状态的物质。

著录项

  • 公开/公告号EP3868407A1

    专利类型

  • 公开/公告日2021-08-25

    原文格式PDF

  • 申请/专利权人 OSAKA UNIVERSITY;

    申请/专利号EP20190873926

  • 发明设计人 FURUKAWA TAKAHISA;CHAYA TARO;

    申请日2019-10-11

  • 分类号A61K45;A61K31/436;A61K38/13;A61P25/06;A61P25/08;A61P25/18;A61P25/20;A61P27/02;C12Q1/48;G01N33/15;G01N33/50;

  • 国家 EP

  • 入库时间 2022-08-24 20:46:33

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