Crosslinking agents for the fabrication of sensing membranes or diffusion controlled membranes of electrochemical sensors containing genipins

摘要

The present invention relates toAccording to the characteristics of extracted and used genipins from plantsAs well as having high biocompatibility compared to conventional toxic crosslinking agentsCompound having amine groupFor example:In response to electron transfer mediatorsThe measurement of the degree of progress of the reaction can be easily confirmed by measuring the UV measurement or the amount of the amine group present.AndWhile maintaining adequate sensitivity to glucoseHaving the advantage of suppressing a rapid decrease in sensor life due to high glucose concentrationThe present invention relates to a crosslinking agent composition for producing a sensing film or a diffusion control film of an electrochemical biosensor containing genipin or its derivative.Diagram