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METHODS FOR PREDICTING THE SURVIVAL TIME OF PATIENTS SUFFERING FROM A MICROSATELLITE UNSTABLE CANCER

机译:预测患有微卫星不稳定癌症的患者存活时间的方法

摘要

The present invention relates to methods for predicting the survival time of patients suffering from a micro satellite unstable cancer. In particular, the present invention relates to a method for predicting the survival time of a patient suffering from a micro satellite unstable cancer comprising i) determining the expression level of at least one gene encoding for an immune checkpoint protein in a tumor tissue sample obtained from the patient, ii) comparing the expression level determined at step i) with a predetermined reference value and iii) concluding that the patient will have a long survival time when the level determined at step i) is lower than the predetermined reference value or concluding that the patient will have a short survival time when the level determined at step i) is higher than the predetermined reference value.
机译:本发明涉及预测患有微卫星不稳定癌症的患者的存活时间的方法。 特别地,本发明涉及预测患有患有微卫星不稳定癌症的患者的存活时间的方法,该患者包含I)确定在获得的肿瘤组织样品中的免疫检查点蛋白的至少一种基因的表达水平 患者II)将步骤i)确定的表达水平与预定的参考值和III进行比较,得出结论,当在步骤i)确定的水平低于预定的参考值或结束时,患者将具有长的存活时间 当步骤i)确定的水平高于预定参考值时,患者将具有短暂的存活时间。

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